IndraLab

EMMAA Dashboard Queries

Test: " GRB2 bound to TNFRSF1A activates RAF1." for MARM_MODEL (PySB)

Path Support
SOS1 ↔ GRB2 → KRAS ↔ RAF1 ↔ RAF1 SOS1 ↔ GRB2
SOS1 binds active GRB2.
SOS1 → KRAS
SOS1 bound to GRB2 activates KRAS.
KRAS ↔ RAF1
Active KRAS binds RAF1.
BRAF ↔ RAF1
BRAF binds RAF1 bound to KRAS.