IndraLab

EMMAA Dashboard Queries

Test: " Kinase-active EGFR activates RAF1." for MARM_MODEL (PySB)

Path Support
EGFR ↔ GRB2 ↔ GRB2 → KRAS ↔ KRAS ↔ RAF1 EGFR ↔ GRB2
EGFR bound to EGFR binds GRB2.
SOS1 ↔ GRB2
SOS1 binds active GRB2.
SOS1 → KRAS
SOS1 bound to GRB2 activates KRAS.
BRAF ↔ KRAS
BRAF binds active KRAS.
BRAF ↔ RAF1
BRAF bound to KRAS binds RAF1.