IndraLab

EMMAA Dashboard Queries

Test: " EGFR increases the amount of MAPK1." for MARM_MODEL (Unsigned Graph)

Path Support
EGFR ↔ GRB2 ↔ GRB2 → KRAS ↔ KRAS → MAP2K1 → MAPK1 EGFR ↔ GRB2
GRB2 binds EGFR.
EGFR binds GRB2.
SOS1 ↔ GRB2
SOS1 binds GRB2.
GRB2 binds SOS1.
SOS1 → KRAS
SOS1 activates KRAS.
BRAF ↔ KRAS
KRAS binds BRAF.
BRAF binds KRAS.
BRAF → MAP2K1
BRAF phosphorylates MAP2K1.
MAP2K1 → MAPK1
MAP2K1 phosphorylates MAPK1.