|EGFR → EGFR → GRB2 → GRB2 → KRAS → KRAS → RAF1 → MAP2K1 → MAPK1||
EGFR → EGFR
EGFR bound to EGFR is a part of EGFR bound to GRB2.
EGFR → GRB2
EGFR bound to GRB2 has a component GRB2.
GRB2 → GRB2
GRB2 is a part of GRB2 bound to SOS1.
SOS1 → KRAS
SOS1 bound to GRB2 activates KRAS.
KRAS → KRAS
KRAS is a part of KRAS bound to RAF1.
KRAS → RAF1
KRAS bound to RAF1 has a component RAF1.
RAF1 → MAP2K1
Active RAF1 phosphorylates MAP2K1.
MAP2K1 → MAPK1
Phosphorylated MAP2K1 phosphorylates MAPK1.