IndraLab

EMMAA Dashboard Queries

Test: "Kinase-active AKT increases the amount of SERPINE1." for PAAD (Unsigned Graph)

Path Support
AKT → BDNF ↔ BDNF ↔ TP53 ↔ KRAS ↔ PIK3CA → SERPINE1 AKT → BDNF
AKT activates BDNF.
RAS ↔ BDNF
RAS binds BDNF.
BDNF binds RAS.
RAS ↔ TP53
TP53 binds RAS.
RAS binds TP53.
TP53 ↔ KRAS ↔ PIK3CA
KRAS → SERPINE1
KRAS activates SERPINE1.