IndraLab

EMMAA Dashboard Queries

Test: "Kinase-active AKT1 leads to the phosphorylation of RPS6KB1 on T412." for RASMODEL (PyBEL) on 2020-02-12

Path Support
AKT1 → MTOR → MTOR → RPS6KB1 AKT1 → MTOR
Active AKT1 phosphorylates MTOR on S2448.
MTOR
MTOR bound to RPTOR and RICTOR and phosphorylated on S2448 is active.
MTOR → MTOR
MTOR is a part of MTOR bound to RPTOR.
MTOR → RPS6KB1
Active MTOR bound to RPTOR phosphorylates RPS6KB1 on T412.