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Test: "SOS1 activates MAPK1." for RASMODEL (PyBEL) on 2020-02-12

Path Support
SOS1 → KRAS → KRAS → RAF1 → MAP2K1 → MAPK1 SOS1 → KRAS
Active SOS1 activates KRAS in the membrane.
KRAS → KRAS
KRAS is a part of KRAS bound to RAF1.
KRAS → RAF1
KRAS bound to RAF1 has a component RAF1.
RAF1 → MAP2K1
Active RAF1 phosphorylates MAP2K1 on S222.
MAP2K1
MAP2K1 phosphorylated on S218 and S222 is active.
MAP2K1 → MAPK1
Active MAP2K1 phosphorylates MAPK1 on Y187.
MAPK1
MAPK1 phosphorylated on T185 and Y187 is active.