IndraLab

EMMAA Dashboard Queries

Test: "Kinase-active BRAF activates ELK1." for RASMODEL (PySB)

Path Support
BRAF → MAP2K1 → MAPK1 → ELK1 BRAF → MAP2K1
Active BRAF phosphorylates MAP2K1 on S218.
MAP2K1 → MAPK1
Active MAP2K1 phosphorylates MAPK1 on T185.
MAPK1 → ELK1
Active MAPK1 phosphorylates ELK1 on S383.