IndraLab

EMMAA Dashboard Queries
Path Support
TSC1 ↔ TSC2 ⊣ RHEB ↔ MTOR → RPS6KB1 TSC1 ↔ TSC2
TSC1 binds TSC2 phosphorylated on S1798, S939, and T1462.
TSC2 ⊣ RHEB
Active TSC2 inhibits RHEB.
RHEB ↔ MTOR
Active RHEB binds MTOR.
MTOR → RPS6KB1
Active MTOR bound to RPTOR phosphorylates RPS6KB1 on T412.