IndraLab

EMMAA Dashboard Queries

Test: "Kinase-active EGFR activates RAC1." for RASMODEL (PySB)

Path Support
EGFR → SRC → TIAM1 → RAC1 EGFR → SRC
EGFR bound to EGFR phosphorylates SRC on Y419.
SRC → TIAM1
Active SRC phosphorylates TIAM1.
TIAM1 → RAC1
Active TIAM1 activates RAC1.