IndraLab

EMMAA Dashboard Queries
Path Support
BRAF ↔ KRAS → BRAF → MAP2K1 → MAPK1 → RPS6KB1 BRAF ↔ KRAS
BRAF binds active KRAS.
SRC → BRAF
Active SRC phosphorylates BRAF bound to KRAS.
BRAF → MAP2K1
Active BRAF phosphorylates MAP2K1 on S222.
MAP2K1 → MAPK1
Active MAP2K1 phosphorylates MAPK1 on Y187.
MAPK1 → RPS6KB1
Active MAPK1 phosphorylates RPS6KB1 on T444.