|EGFR → SRC → BRAF → MAP2K1 → MAPK1 → ELK1||
EGFR → SRC
EGFR bound to EGFR phosphorylates SRC on Y419.
SRC → BRAF
Active SRC phosphorylates BRAF bound to KRAS.
BRAF → MAP2K1
Active BRAF phosphorylates MAP2K1 on S218.
MAP2K1 → MAPK1
Active MAP2K1 phosphorylates MAPK1 on T185.
MAPK1 → ELK1
Active MAPK1 phosphorylates ELK1 on S383.