IndraLab

EMMAA Dashboard Queries
Path Support
RPS6KB1 → IRS1 ↔ PIK3CA → phosphatidylinositol trisphosphate ↔ AKT1 → MTOR → RPS6KB1 RPS6KB1 → IRS1
RPS6KB1 phosphorylates IRS1.
IRS1 ↔ PIK3CA
PIK3CA binds IRS1.
IRS1 binds PIK3CA.
PIK3CA → phosphatidylinositol trisphosphate
PIK3CA increases the amount of phosphatidylinositol trisphosphate.
phosphatidylinositol trisphosphate ↔ AKT1
Phosphatidylinositol trisphosphate binds AKT1.
AKT1 binds phosphatidylinositol trisphosphate.
AKT1 → MTOR
AKT1 phosphorylates MTOR.
MTOR → RPS6KB1
MTOR phosphorylates RPS6KB1.