IndraLab

EMMAA Dashboard Queries

Test: "IRS1 leads to the phosphorylation of AKT1 on S473." for RASMODEL (Unsigned Graph)

Path Support
IRS1 ↔ PIK3CA → phosphatidylinositol trisphosphate ↔ AKT1 IRS1 ↔ PIK3CA
PIK3CA binds IRS1.
IRS1 binds PIK3CA.
PIK3CA → phosphatidylinositol trisphosphate
PIK3CA increases the amount of phosphatidylinositol trisphosphate.
phosphatidylinositol trisphosphate ↔ AKT1
Phosphatidylinositol trisphosphate binds AKT1.
AKT1 binds phosphatidylinositol trisphosphate.