IndraLab

EMMAA Dashboard Queries

Test: "Phosphatase-active PTEN inhibits MTOR." for RASMODEL (Unsigned Graph)

Path Support
PTEN ⊣ phosphatidylinositol trisphosphate ↔ AKT1 → MTOR PTEN ⊣ phosphatidylinositol trisphosphate
PTEN decreases the amount of phosphatidylinositol trisphosphate.
phosphatidylinositol trisphosphate ↔ AKT1
Phosphatidylinositol trisphosphate binds AKT1.
AKT1 binds phosphatidylinositol trisphosphate.
AKT1 → MTOR
AKT1 phosphorylates MTOR.