IndraLab

EMMAA Dashboard Queries
Path Support
PTEN ⊣ phosphatidylinositol trisphosphate ↔ AKT1 → MTOR ⊣ PPP2CA → IRS1 ↔ IRS1 ↔ EGFR ↔ EGFR PTEN ⊣ phosphatidylinositol trisphosphate
PTEN decreases the amount of phosphatidylinositol trisphosphate.
phosphatidylinositol trisphosphate ↔ AKT1
Phosphatidylinositol trisphosphate binds AKT1.
AKT1 binds phosphatidylinositol trisphosphate.
AKT1 → MTOR
AKT1 phosphorylates MTOR.
MTOR ⊣ PPP2CA
MTOR inhibits PPP2CA.
PPP2CA → IRS1
PPP2CA dephosphorylates IRS1.
SOS1 ↔ IRS1
SOS1 binds IRS1.
IRS1 binds SOS1.
SOS1 ↔ EGFR
SOS1 binds EGFR.
EGFR binds SOS1.
EGF ↔ EGFR
EGFR binds EGF.
EGF binds EGFR.