IndraLab

EMMAA Dashboard Queries

Test: "Kinase-active MTOR activates SRC." for RASMODEL (Unsigned Graph)

Path Support
MTOR ⊣ PPP2CA → IRS1 ↔ IRS1 ↔ EGFR → SRC MTOR ⊣ PPP2CA
MTOR inhibits PPP2CA.
PPP2CA → IRS1
PPP2CA dephosphorylates IRS1.
SOS1 ↔ IRS1
SOS1 binds IRS1.
IRS1 binds SOS1.
SOS1 ↔ EGFR
SOS1 binds EGFR.
EGFR binds SOS1.
EGFR → SRC
EGFR phosphorylates SRC.