IndraLab

EMMAA Dashboard Queries

Test: "SOS1 increases the amount of RAC1." for RASMODEL (PyBEL) on 2020-02-12

Path Support
SOS1 → EGFR → EGFR → EGFR → SRC → TIAM1 → RAC1 SOS1 → EGFR
SOS1 is a part of EGFR bound to SOS1.
EGFR → EGFR
EGFR bound to SOS1 has a component EGFR.
EGFR → EGFR
EGFR is a part of EGFR bound to EGFR.
EGFR → SRC
EGFR bound to EGFR phosphorylates SRC on Y419.
SRC
SRC phosphorylated on Y419 is active.
SRC → TIAM1
Active SRC phosphorylates TIAM1.
TIAM1
Phosphorylated TIAM1 is active.
TIAM1 → RAC1
Active TIAM1 activates RAC1.